큰 뇌하수체 선종의 경접형동 접근법의 치료 경험

• 영문명: Clinical Experience of Large Pituitary Adenomas Treated by Transsphenoidal Approach
• 발행기관: 대한두개저학회
• 저자명: 양승호(Seung-Ho Yang) 김일섭(Il Sup Kim) 홍재택(Jae Taek Hong) 성재훈(Jae Hoon Sung) 손병철(Byung Chul Son) 이상원(Sang Won Lee)
• 간행물 정보: 『대한두개저학회지』제2권 제1호, 23~27쪽, 전체 5쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2007.10.30

영문 초록

Objective The purpose of this study is to determine the feasibility of transsphenoidal approach (TSA) and staged or repeated TSA for large pituitary adenoma (LPA) and remnant or recurrent PA. Methods Eighteen LPAs underwent TSA surgery from February 2002 to December 2006. Eleven cases were non-functioning adenomas, 5 cases were growth hormone secreting adenomas and 2 cases were pituitary apoplexy. Mean size of tumor was 38x28x30mm. All patients were initially operated via TSA. Results Total removal was performed in 8 patients (44.4%). Subtotal removal was done in 8 patients (44.4%) by the initial TSA, two patients in which underwent repeated TSA due to postoperative tumor bleeding. The visual and hormonal symptoms were improved in 13 patients (72.2%) after the surgery. Six patients out of 8 with subtotal removal underwent the staged operation. Two patients with tumor recurrence underwent repeated TSA, 18 and 26 months respectively after the initial TSA. All patients with growth hormone-secreting PA achieved the normalization of growth hormone. Conclusion The staged and repeated TSA is one of the feasible option for the treatment of LPA and residual or recurrent PA with acceptable surgical morbidity and mortality.

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키워드

Pituitary adenomas Operation Transshenoidal approach Recurrence Complication