학술논문
Integrated cryoEM imaging center at Seoul National University, Korea
이용수 4
- 영문명
- 발행기관
- 한국구조생물학회
- 저자명
- Miji Jeon Jun Bae Park Hansol Lee Gyuhee Kim Eung Baek Kim Mingyu Jung Soung-Hun Roh
- 간행물 정보
- 『Biodesign』Vol 9, No 4, Dec, 72~77쪽, 전체 6쪽
- 주제분류
- 자연과학 > 생물학
- 파일형태
- 발행일자
- 2021.12.31
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국문 초록
영문 초록
The Center for Macromolecular and Cell Imaging (CMCI) is a core facility equipped with multiple cryo-capable electron microscopes including a 200 kV Thermofisher Glacios, 200 kV JEOL JEM2100Plus and 120 kV FEI TECNAI with direct electron detector technologies. The center also has auxiliary equipment for optimal specimen preparation, such as for protein purification, tissue culture, grid preparation and vitrification. The center offers to the scientific community the best practice of cutting-edge cryogenic electron microscopy (cryoEM) technology for specimen optimization, high-resolution data collection and structure determination. The center also develops the strategy of an integrated cryoEM imaging platform to visualize molecular architectures from purified proteins to cells.
목차
INTRODUCTION
CONCLUSION
ACKNOWLEDGEMENTS
REFERENCES
키워드
해당간행물 수록 논문
- Purification, crystallization, and preliminary X-ray diffraction analysis of an S-formylglutathione hydrolase (VaSFGH) homolog from Variovorax sp. PAMC 28711
- Integrated cryoEM imaging center at Seoul National University, Korea
- Crystallization and preliminary diffraction analysis of the phosphatase domain of PTPN14 in the human papillomavirus E7 binding-defective mutant form
- Crystal structure of the Fab fragment of burosumab, the first-in-class anti-FGF23 medicine for treating X-linked hypophosphatemia and tumor-induced osteomalacia
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