헤드스페이스-가스크로마토그래피-질량분석법에 의한 체모 중포름알데하이드 측정법 연구

• 발행기관: 한국환경보건학회
• 저자명: 신호상(Ho-Song Shin) 안혜실(Aye-sil Ahn)
• 간행물 정보: 『1. 한국환경보건학회지』제32권 제1호, 67~70쪽, 전체 0쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 2006.02.28

영문 초록

A gas chromatography/mass spectrometric method was developed for the determination of formaldehyde in hair. 0.3 mg of hair was placed in 10 ml headspace vial. 1.5 mM pentafluorophenylhydrazine solution (pH 2) in 0.03 M phosphoric acid and 20 l of 500 mg/l acetone-d6 as internal standard were added in vial and sealed tightly with cap. The solution was heated for 30 min at 90oC in heating block. The extraction, the derivatization and the evaporation were performed simultaneously. After heating of the solution, 0.5 ml of headspace was taken up and analyzed by gas chromatography-mass spectrometry (GC-MS). Low limit of detection (LOD) and Low limit of quantitation (LOQ) of formaldehyde were 0.5 and 1.5 ng/g, respectively. The method was used to analyze formaldehyde in rat hair after oral exposure. The developed method may be valuable to be used to analyze formaldehyde in human hair.

목차

Ⅰ. 서론

Ⅱ. 실험

Ⅲ. 결과 및 고찰

Ⅳ. 고찰

키워드

gas chromatography-mass spectrometer formaldehyde hair exposure indicator