백출(Atractylodis Rhizoma Alba)의 품질평가를 위한 지표성분 분석법 평가

• 영문명: Development of HPLC Method for Quality Assessment of Marker Components in Atractylodis Rhizoma Alba
• 발행기관: 한국자원식물학회
• 저자명: 이재웅(Jae-Woong Lee) 김준희(Joon-Hee Kim) 강병만(Byoung-Man Kang) 안병관( Byung-Kwan Ahn)
• 간행물 정보: 『한국자원식물학회지』제34권 제1호, 52~58쪽, 전체 7쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2021.02.28

영문 초록

Homogenization of quality was important in order to use herbal medicines as pharmaceuticals. To solve this problem, it was important to establish quality standards. Atractylodis Rhizoma Alba has no quantitative method in the Korean Pharmacopoeia. Thus, we have researched to improve the quality evaluation method of Atractylodis Rhizoma Alba with an HPLC. Atractylenolide Ⅲ and atracylodin were selected as potential marker compounds. This analytical procedure was subject to validation. According to validation guideline of South Korea’s Ministry of Food and Drugs Safety, the specificity, linearity, precision, range, quantitative limits, detection limits and accuracy were measured. Because the specificity, linearity, precision, range, quantitative limits, detection limits and accuracy meet criteria of the guideline, the analytic method was validated. With this analysis, Atractylodis Rhizoma Alba and Atractylodis Rhizoma analyzed. As a result, both atractylenolide Ⅲ and atracylodin appear to be suitable standard compounds. it confirmed that tractylodes Rhizome, similar to Atractylodes Rhizome Alba, could be distinguished.

목차

서 언

재료 및 방법

결과 및 고찰

키워드

Analysis Atractylenolide Ⅲ Atractylodes macrocephala Koidzum Atracylodin