나노물질을 이용한 질량분석 기술 개발동향

• 영문명: Mass spectrometry based on nanomaterials
• 발행기관: 한국세라믹학회
• 저자명: 박종민(Jong-Min Park) 노주윤(Joo-Yoon Noh) 김문주(Moon-Ju Kim) 변재철(Jae-Chul Pyun)
• 간행물 정보: 『세라미스트』제21권 제3호, 249~269쪽, 전체 21쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2018.09.30

영문 초록

In conventional MALDI-TOF mass spectrometry, analyte molecules are known to be ionized by mixing with organic matrix molecules. As the organic matrix molecules are made into small fragments, they generate unreproducible mass peaks such that MALDI-TOF mass spectrometry is nearly impossible in the low mass-to-charge (m/z) range (< 1000). Additionally, the dried sample mixed with matrix were made as inhomogeneous crystal on metal plate. When the laser radiation was made on the sample crystal, the amount of generated sample ion was observed to be quite different according to the radiation point. Therefore, the quantitative analysis was very difficult even for the sample spots at the same concentration for the conventional MALDI-TOF mass spectrometry. In this work, we present laser desorption/ionization (LDI) mass spectrometry based on solid-matrices for the quantitative analysis of small molecules in the low m/z range by using MALDI-TOF mass spectrometry: (1) Carbon based nanostructures; (2) Semiconductor based nanomaterials; (3) Metal based nanostructures.

목차

1. 서론

2. 본론

3. 결론

참고문헌

키워드

LDI-mass spectrometry MALDI-TOF solid-matrix quantitative analysis