Efect of Herbal Medicinal Preparations Containing Ginseng on Learning and Memory in Kainate-induced Seizures

• 영문명: Efect of Herbal Medicinal Preparations Containing Ginseng on Learning and Memory in Kainate-induced Seizures
• 발행기관: 한국자원식물학회
• 저자명: Park, Jin-Kyu Jin, Sung-Ha Park, Kum-Hee Ko, Ji-Hun Ki yeul Nam Yang, Deok-Chun Park, Eun-Kyung
• 간행물 정보: 『한국자원식물학회 학술심포지엄』2000년도 제7차 국제 심포지움(생약자원개발에 관한연구) 및 추계정기 학술발표회 초록집, 84~95쪽, 전체 12쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2000.10.31

영문 초록

Coleus forskohlii Briq. of the family Lamiaceae yields a valuable secondary metabolite known as forskolin which is a labdane diterpenoid. Coleus forskohlii is the only known source of this compound. Forskolin is used in medicine for the treatment of glaucoma, congestive cardiomyopathy and asthma. Morphogenic callus was induced from young leaves on MS medium augmented with NAA and BA. These calli, when subcultured on MS with KN alone gave rise to shoots. The regenerated shoot developed good root system on MS medium fortified with NAA. The fully grown plantlets were transferred to soil for acclimatization. Coleus plant is mainly infected by a fungi Lasiodiplodia theobromae which causes root of disease. The fungal culture filterate (FCF) of Lasiodiplodia theobromae, has been used in regeneration media to find the MIC and further to select resistant plants to the pathogen. In the present study 40% FCF in the medium showed maximum inhibition and is there fore considered as the MIC level of Coleus forskohlii. This data could prove to be useful for the future for selecting a resistant C,forskohlii plant against the root disease caused by L.theobromae.