Ethnopharmacology, bioactivities and chemical constituents of some anti-cancer plants in Malaysia

• 영문명: Ethnopharmacology, bioactivities and chemical constituents of some anti-cancer plants in Malaysia
• 발행기관: 한국자원식물학회
• 저자명: Chooi, Ong-Hean
• 간행물 정보: 『한국자원식물학회 학술심포지엄』1999년도 The 6th International Symposium on the Development of Anti-Cancer Resource from Plants, 90~109쪽, 전체 20쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 1999.10.31

영문 초록

A new lignan named as hibiscuside, (+) pinoresinol 4-O-[-glucopyranosyl (12) -rhamnoside] (1), and a known lignan, syringaresinol (2) were isolated from the root bark of Hibiscus syriacus together with two feruloyltyramines (3,4) and three known isoflavonoids (5,6,7). The structures of these compounds have been established on the basis of their NMR, Mass, UV spectra. Among these phenolic compounds,6-O-acetyl daidzin (5), 6-O- acetyl genistin (6), and 3-hydroxy daidzein (7) with IC50 values of 8.2, 10.6, and 4.1 M, respectively, significantly inhibited lipid peroxidation in rat liver microsomes Hibiscuside (1), E and Z-N-feruloyl tyramines (3,4) exhibited moderate antioxidant activity.