Improving Effects of Brassica oleracea L. var. italica Sprout Extract on Alcoholic Liver Dysfunction

• 발행기관: 한국자원식물학회
• 저자명: Min Jeong Kim Hye Jeong Yang Hak Yong Lee Young Mi Park Dong Yeop Shin Yang Hee Lee Yang Gyu Kang Tae Su Kim Sung Pyo Lee Kwang-Hyun Park
• 간행물 정보: 『한국자원식물학회지』제33권 제3호, 163~169쪽, 전체 7쪽
• 주제분류: 농수해양 > 기타농수해양
• 파일형태: PDF
• 발행일자: 2020.06.30

영문 초록

Alcoholic fatty liver disorder has become a frequent health concern worldwide. To investigate the effects ofBrassica oleracea (B. oleracea) sprout extract (BOE), the present study was designed with alcoholic fatty liver in the rat. Initially, the effects of BOE on liver parameters were examined. Male rats were divided into five groups. The normal controlgroup was fed the normal diet, and the BOE group was fed the high fat diet and ethanol with/without BOE for 4 weeks. After4 weeks feeding period, rats were sacrificed and their livers and blood were used for fatty liver-related biomarkers analyses. As a result, BOE ameliorated fatty liver-related enzymes profiles in liver tissues and also reduced blood alcoholconcentration in rat model. We demonstrated that BOE protected the high fat diet and alcohol-induced fatty liver in ratmodel. Furthermore, BOE increased detoxificative abilities against alcohol.

목차

Introduction

Materials and Methods

Results and Discussion

Acknowledgement

Conflict of Interest

References

키워드

Alcoholic liver dysfunction Brassica oleracea sprout extract Fatty liver High fat diet