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학술논문

Salivary biomarkers in oral squamous cell carcinoma

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영문명
발행기관
대한구강악안면외과학회
저자명
Truc Thi Hoang Nguyen Buyanbileg Sodnom-Ish Sung Weon Choi Hyo-Il Jung Jaewook Cho Inseong Hwang Soung Min Kim
간행물 정보
『대한구강악안면외과학회지』대한구강악안면외과학회지 제46권 제5호, 301~312쪽, 전체 12쪽
주제분류
의약학 > 내과학
파일형태
PDF
발행일자
2020.10.30
4,240

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국문 초록

영문 초록

In disease diagnostics and health surveillance, the use of saliva has potential because its collection is convenient and noninvasive. Over the past two decades, the development of salivary utilization for the early detection of cancer, especially oral cavity and oropharynx cancer has gained the interest of the researcher and clinician. Until recently, the oral cavity and oropharynx cancers are still having a five-year survival rate of 62%, one of the lowest in all major human cancers. More than 90% of oral cancers are oral squamous cell carcinoma (OSCC). Despite the ease of accessing the oral cavity in clinical examination, most OSCC lesions are not diagnosed in the early stage, which is suggested to be the main cause of the low survival rate. Many studies have been performed and reported more than 100 potential saliva biomarkers for OSCC. However, there are still obstacles in figuring out the reliable OSCC salivary biomarkers and the clinical application of the early diagnosis protocol. The current review article discusses the emerging issues and is hoped to raise awareness of this topic in both researchers and clinicians. We also suggested the potential salivary biomarkers that are reliable, specific, and sensitive for the early detection of OSCC.

목차

I. Introduction
II. Salivary Biomarkers
III. Liquid Biopsy of OSCC
IV. Relations with Other Serum Biomarkers
V. Suggested Salivary Biomarkers, Present and Future
VI. Conclusion with Future Trends
References

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APA

Truc Thi Hoang Nguyen,Buyanbileg Sodnom-Ish,Sung Weon Choi,Hyo-Il Jung,Jaewook Cho,Inseong Hwang,Soung Min Kim. (2020).Salivary biomarkers in oral squamous cell carcinoma. 대한구강악안면외과학회지, 46 (5), 301-312

MLA

Truc Thi Hoang Nguyen,Buyanbileg Sodnom-Ish,Sung Weon Choi,Hyo-Il Jung,Jaewook Cho,Inseong Hwang,Soung Min Kim. "Salivary biomarkers in oral squamous cell carcinoma." 대한구강악안면외과학회지, 46.5(2020): 301-312

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