비 인두암 체적 조절 호형 방사선 치료의 선량 계산 격자 크기에 따른 선량 체적 지수와 방사선 생물학적 지수의 평가

• 영문명: Evaluation of Dose Volume and Radiobiological Indices by the Dose Calculation Grid Size in Nasopharyngeal Cancer VMAT
• 발행기관: 대한방사선과학회(구 대한방사선기술학회)
• 저자명: 강동진(Dong-Jin Kang) 정재용(Jae-Yong Jung) 신영주(Young-Joo Shin) 민정환(Jung-Whan Min) 심재구(Jae-Goo Shim) 박소현(So-Hyun Park)
• 간행물 정보: 『방사선기술과학』방사선기술과학 제43권 제4호, 265~272쪽, 전체 8쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2020.08.31

영문 초록

The purpose of this study was to investigate the dose-volume indices and radiobiological indices according to the change in dose calculation grid size during the planning of nasopharyngeal cancer VMAT treatment. After performing the VMAT treatment plan using the 3.0 ㎜ dose calculation grid size, dose calculation from 1.0 ㎜ to 5.0 ㎜ was performed repeatedly to obtain a dose volume histogram. The dose volume index and radiobiological index were evaluated using the obtained dose volume histogram. The smaller the dose calculation grid size, the smaller the mean dose for CTV and the larger the mean dose for PTV. For OAR of spinal cord, brain stem, lens and parotid gland, the mean dose did not show a significant difference according to the change in dose calculation grid size. The smaller the grid size, the higher the conformity of the dose distribution as the CI of the PTV increases. The CI and HI showed the best results at 3.0 ㎜. The smaller the dose calculation grid size, the higher the TCP of the PTV. The smaller the dose calculation grid size, the lower the NTCP of lens and parotid. As a result, when performing the nasopharynx cancer VMAT plan, it was found that the dose calculation grid size should be determined in consideration of dose volume index, radiobiological index, and dose calculation time. According to the results of various experiments, it was determined that it is desirable to apply a grid size of 2.0 - 3.0 ㎜.

목차

Ⅰ. 서 론

Ⅱ. 대상 및 방법

Ⅲ. 결 과

Ⅳ. 고찰 및 결론

REFERENCES

키워드

선량 계산 격자 크기 조형 지수 균일 지수 종양 제어 확률 정상 조직 합병증 확률 Dose calculation grid size Conformity index (CI) Homogeneity index (HI) Tumor control probability (TCP) Normal tissue complication probability (NTCP)