상악동에 발생한 대세포 신경내분비 암종 1례

• 영문명: A Case of Large Cell Neuroendocrine Carcinoma of the Maxillary Sinus
• 발행기관: 대한두경부종양학회
• 저자명: 이윤재(Yun Jae Lee) 정진혁(Jin Hyeok Jeong,) 오영하(Young Ha Oh) 지용배(Yong Bae Ji)
• 간행물 정보: 『대한두경부종양학회지』제35권 제2호, 45~49쪽, 전체 5쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2019.11.30

영문 초록

Large cell neuroendocrine carcinoma is a rare epithelial neuroendocrine malignancy and is preferentially located in gastrointestinal tract and pancreas. Cases of large cell neuroendocrine carcinoma have been reported in many other locations, including the thymus, gallbladder, prostate, larynx, salivary glands, nasopharynx, tonsil and mastoid. However, primary sinonasal large cell neuroendocrine carcinoma never have been reported in Korea. We experienced a case of primary large cell neuroendocrine carcinoma arising from left maxillary sinus recently. A 82-year-old male patient presented with nasal obstruction and epistaxis. The biopsy revealed large cell neuroendocrine carcinoma with poor differentiation. After a general evaluation, the patient was staged as cT3N0M0. The patient was treated by combined radiotherapy and chemotherapy. We report this rare case with literature review.

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키워드

Large cell neuroendocrine carcinoma Paranasal sinus