흰쥐 난자형성 세포의 알리인 방어효과

• 영문명: Radioprotection of Alliin in Oogenesis Cells of a White Rat
• 발행기관: 대한방사선과학회(구 대한방사선기술학회)
• 저자명: 지태정(JI Tae-Jeong)
• 간행물 정보: 『방사선기술과학』방사선기술과학 제41권 제5호, 471~478쪽, 전체 8쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2018.10.30

영문 초록

Oogenesis process of ovary produces a lot of undifferentiated cells. Especially, the radiation exposure of early immature cells in the process of growth to oocyte causes serious disabilities. This study examined the radiation damage mechanism of undifferentiated cells and organelles in oogenesis process, and the radioprotection after injection of alliin. The ultrastructure after 7Gy X-ray irradiation on the white rat was observed in the experiment. The results is as follows. It was observed that the nucleus membrane of an oogonium was damaged and vacuolated in the several parts after 15 days of irradiation. The damage of mitochondria membrane and flow in cytoplasm after 20 and 30 days was found in the oogonium. After 40 days observation, peroxidation of fat droplets was found and organelles were tangled each other in ovary tissue. The partial damage of nuclear membrane in oogonium past 15 days after injection of alliin was found, but decreased remarkably. Mitochondria, Golgi body, and rough endoplasmic reticulum were also clearly observed, therefore, radioprotection effects in alliin was confirmed partially.

목차

Ⅰ. 서 론

Ⅱ. 재료 및 방법

Ⅲ. 결 과

Ⅳ. 고 찰

Ⅴ. 결 론

키워드

Ovary Radiation Alliin Radioprotection Mitochondria 난소 방사선 알리인 방어효과 미토콘드리아