전신방사선조사 시 선속 스포일러에 따른 선량 분포 및 영향 평가

• 영문명: Beam Spoiler-dependent Total Body Irradiation Dose Assessment
• 발행기관: 대한방사선과학회(구 대한방사선기술학회)
• 저자명: 이동연(Dong-Yeon Lee) 김정훈(Jung-Hoon Kim)
• 간행물 정보: 『방사선기술과학』방사선기술과학 제41권 제2호, 141~148쪽, 전체 8쪽
• 주제분류: 의약학 > 방사선과학
• 파일형태: PDF
• 발행일자: 2018.04.30

국문 초록

This study examined the properties of photons and the dose distribution in a human body via a simulation where the total body irradiation(TBI) is performed on a pediatric anthropomorphic phantom and a child size water phantom. Based on this, we tried to find the optimal photon beam energy and material for beam spoiler. In this study, MCNPX (Ver. 2.5.0), a simulation program based on the Monte Carlo method, was used for the photon beam analysis and TBI simulation. Several different beam spoiler materials (plexiglass, copper, lead, aluminium) were used, and three different electron beam energies were used in the simulated accelerator to produce photon beams (6, 10, and 15 MeV). Moreover, both a water phantom for calculating the depth-dependent dosage and a pediatric anthropomorphic phantom for calculating the organ dosage were used. The homogeneity of photon beam was examined in different depths for the water phantom, which shows the 20%–40% difference for each material. Next, the org an doses on pediatric anthro-pomorphic phantom were examined, and the results showed that the average dose for each part of the body was skin 17.7 Gy, sexual gland 15.2 Gy, digestion 13.8 Gy, liver 11.8 Gy, kidney 9.2 Gy, lungs 6.2 Gy, and brain 4.6 Gy. Moreover, as for the organ doses according to materials, the highest dose was observed in lead while the lowest was ob-served in plexig lass. Plexig lass in current use is considered the most suitable material, and a 6 or 10 MV photon energ y plan tailored to the patient condition is considered more suitable than a higher energy plan.

목차

Ⅰ. INTRODUCTION

Ⅱ. MATERIALS AND METHODS

Ⅲ. RESULTS

Ⅳ. DISCUSSION

Ⅴ. CONCLUSION

키워드

Leukaemia Total body irradiation Beam spoiler MCNPX Dose assessment 백혈병 전신방사선조사 빔 스포일러 MCNPX 선량평가