눈꽃동충하초(paecilomyces japonica)추출물의 지질대사 및 당대사에 미치는 영향

• 영문명: Antidiabetic and Lipid Metabolism Effect of Paediomyces Japonica in Streptozotocin-Induced Diabetic Rats
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: 김옥경(Ok Kyung Kim)
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제27권 제4호, 494~500쪽, 전체 7쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2009.12.31

영문 초록

This study was carried to investigate the antidiabetic and lipid metabolism of water extract paecilomyces japonica(PJ) in Streptozotocin (STZ) induced diabetic rats. Diabetes were induced by intravenous injection of STZ at a dose of 42㎎/㎏ dissolved in citrate buffer. The water extract of paecilomyces japonica were orally administrated once a day for 7 days at a dose of 500㎎/㎏ or 1,000㎎/㎏. The contents of serum glucose, triglyceride(TG), total cholesterol were significantly decreased in PJ treated group compared to the those of STZ-control group. The content of hepatic glycogen and activities of glucose-6-phosphate dehydrogenase(G-6-PDH), glucokinase(GK) were significantly increased, but activity of glucose-6-phoshatase(G-6-Pase) was significantly decreased in PJ treated group compared to the those of STZ-control group. These results indicated that water extract of paecilomyces japonica would have antidiabetic and lipid metabolism effect in STZ-induced diabetic rats.

목차

1. 서 론

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3. 결과 및 고찰

4. 결 론

감사의 글

참고문헌

키워드

streptozotocin triglyceride total cholesterol antidiabetic effects paecilomyces japonica