Preparation of Mesoporous Materials and Thin Films It s Application for DNA Sensor

• 영문명: Preparation of Mesoporous Materials and Thin Films It s Application for DNA Sensor
• 발행기관: 한국응용과학기술학회 (구.한국유화학회)
• 저자명: Han SeungJun Park KeunHo Heo SoonYoung Kim ByungKwan Lee Soo Kim JinHeung
• 간행물 정보: 『한국응용과학기술학회지』한국유화학회지 제21권 제4호, 345~351쪽, 전체 7쪽
• 주제분류: 공학 > 화학공학
• 파일형태: PDF
• 발행일자: 2004.12.31

영문 초록

Highly ordered pure-silica MCM-41 materials possessing well-defined morphology have been successfully prepared with surfactant used as a template. The fabrication of mesoporous silica has received considerable attention due to the need to develop more efficient materials for catalysis, separations, and chemical sensing. The surface modified MCM-41 was used as anadsorbent for biomolecules. Silica-supported organic groups and DNA adsorption on surface modified MCM-41 were investigated by FT-IR and UV-Vis spectrometer, respectively. The use of MCM-41 as the modification of electrode surfaces were investigated electrochemical properties of metal mediators with biomolecules. The modified ITO electrodes increased peak currents for a redox process of [Ru(bpy)_3]^{2+} relative to the bare electrode. The electrochemical detection of DNA by cyclic voltammetry when the current is saturated in the presence of the mediator appeared more sensitive due to a higher catalytic current on the MCM-41 supported electrodes modified by carboxylic acid functional groups. The carboxyl or amine groups on the surface of MCM-41 interact and react with the -NH2 groups of guanine and backbone, respectively. Highly ordered mesoporous materials with organic groups could find applications as DNA sensors.

키워드

MCM-41 sol-gel surface modification