Bleomycin, Mitomycin C 및 Cadmium에 의한 CHO 세포의 적응반응

• 영문명: Adaptive Response in CHO Cells by Bleomycin, Mitomycin C and Cadmium
• 발행기관: 한국환경보건학회
• 저자명: 김양지 한정호 정해원
• 간행물 정보: 『1. 한국환경보건학회지』제18권 제2호, 117~124쪽, 전체 8쪽
• 주제분류: 공학 > 환경공학
• 파일형태: PDF
• 발행일자: 1992.11.30

영문 초록

Pretreatment with low concentration of Bleomycin and Cadmium rendered Chinese Hamster Ovary Cells more resistant to the induction of chromosome aberration by subsequent high concentration of same agent, however Mitomycin C did not function in that way. The cells pre-exposed to low dose of Cadmitim did not show cross-resistance to challenge dose of Mitomycin C for the induction of chromosome aberration, but cells pre-exposed to Bleomycin showed cross resistance. And the cells pre-exposed to low dose of Mitomycin C showed cross resistance to challenge of Bleomycin, but Cadmium did not.