구강편평상피암에 관한 임상적 연구

• 영문명: A clinical study on squamous cell carcinoma of the oral cavity
• 발행기관: 대한구강악안면외과학회
• 저자명: Sun Youl Ryu(柳善烈) Teruo Amagasa(天笠光雄) Shigetoshi Shioda(鹽田重利)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제16권 제2호, 65~79쪽, 전체 15쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 1990.04.30

영문 초록

For the purpose of prevention, early diagnosis and improvement in treatment result of oral cancer, clinical statistical study was performed about clinical and histopathologic findings and treatment of 52 cases of oral squamous cell carcinoma to have been diagnosed and treated in the First Department of Oral Surgery, Faculty of Dentistry, Tokyo Medical and Dental University from the 1st of November, 1988 to the 31th of October, 1989. The results were as follows: 1. In the site distribution, 25 cases(48%) of the tongue was the most frequently involved site, followed by the lower alveolus and gingiva with 7 cases, the buccal mucosa and the maxillary sinus with each 5 cases, the upper alveolus and gingiva with 4 cases, and the floor of mouth and the oropharynx with each 3 cases. 2. Oral squamous cell carcinoma occured more often in males than females with a ratio of 1.5:1, and 88.4% occured between 40 and 79 years of age with a median of 59.7 years. 3. The majority of initial symptom was pain (44.2%) and swelling (28.8%), and 55.8% of patients was visited within 3 months after onset of initial symptom. Thirty-two patients (61.5%) introduced by dentist and 36.5% had previous surgical treatment at another hospital. 4. In the TNM classification, T2 was prominent with 26 cases (50.0%) and NO was 38 cases(73.1%). In the clinical stage grouping, stage Ⅱ was prominent with 22 cases (44.2%). 5. In the mode of growth of the lesions, ulcerative type was prominent with 15 cases (28.3%), and followed by granular, papillary, leukoplakic, deeply infiltrating and erosive type in order of frequency. Large size of the primary tumor was popular in the deeply infiltrating and granular type, and the cervical metastasis was prominent in the ulcerative type. 6. In the degree of differentiation, well differentiated type was prominent with 26 cases (53.8%). 7. In the treatment of primary lesion, the treatment consisted mainly of surgical therapy was prominent with 36 cases (67.3%). Nineteen cases (36.5%) of single therapy and 33 cases (63.2%) of combined therapy was carried out, and rising tendency of combined therapy was observed according to the stage increment. 8. Partial resection or total excision or extended total excision was selected for the method of surgery of the primary lesion by the case, and combined surgery, radiotherapy and regional chemotherapy was applied to the cancer of the upper alveolus and gingiva and the maxillary sinus. Reconstructive surgery was performed in 48.6% of the surgery 35 cases. 9. Radiation therapy was carried in 52.9%, chemotherapy in 53.8%, and immunotherapy in 73.1% of patients. 10. Neck dissection was performed in 21 cases (60.0%) of the surgery 35 cases and the accuracy rate between clinical and histopathological diagnosis about cervical metastasis was 76.2%.

목차

Abstract

I. 서론

II. 연구대상 및 방법

III. 연구 결과

IV. 고찰

V. 결론

참고문헌