백서 하악골에서 신연골형성술시 압축력의 효능에 관한 실험적 연구

• 영문명: EXPERIPENTAL STUDY OF ROLE OF COMPRESSION FORCES ON DISTRACTION OSTEOGENESIS ON THE RAT MANDIBLE
• 발행기관: 대한구강악안면외과학회
• 저자명: 강항립(Hang-Rip Kang) 김철훈(Cheol-Hun Kim) 신상훈(Sang-Hoon Shin) 정인교(In-Kyo Chung) 김욱규(Uk-Kyu Kim)
• 간행물 정보: 『대한구강악안면외과학회지』대한구강악안면외과학회지 제30권 제5호, 368~379쪽, 전체 12쪽
• 주제분류: 의약학 > 내과학
• 파일형태: PDF
• 발행일자: 2004.10.30

영문 초록

Distraction osteogenesis is a biologic process of new bone formation between the surfaces of bone segments that are gradually separated by incremental traction. Distraction osteogenesis is clinically applied as a new treatment modality of mandibular hypoplasia or bony defect area in maxillofacial area by many studies of distraction devices and method. But disadvantage of distraction osteogenesis shows unfavorably long consolidation period and relapse tendency. Therefore. this experiment was designed to investigate the effectiveness of combined application of distraction and compression force for improving of bone quality and shortening of treatment period during distraction osteogenesis. Twenty-one Sprague-Dawley rats with 300~350gm were used. These were divided into two group as distraction group and combination group was applied with compression force in the consolidation period. The rat were sacrificed for gross finding, radiographic and histologic findings. at 2, 4 weeks after distraction. The result were follow : 1. On radiographic finding, all experimental groups appeared more radiopacity than control groups both at 2, 4 weeks after distraction. 2. On histologic finding, trabeculae of bone and mature lamellar bone were showed increasingly in experimental group. Ossification occured rapidly. From this study, we may suggest that compression force application in consolidation period during distraction osteogenesis can be useful method improve bone quality and to shorten the treatment period. But more experimental and clinical studis are necessitated on effects of compression force application during distraction osteogenesis.

키워드

Distraction osteogenesis Compression force