타액선 악성종양의 경부 림프절 전이의 위험 요소

• 영문명: Risk Factors of Nodal Metastasis in Salivary Gland Cancer
• 발행기관: 대한두경부종양학회
• 저자명: 이시형(Si Hyung Lee) 남순열(Soon Yuhl Nam) 최승호(Seung Ho Choi) 박정제(Jung Je Park) 김찬종(Chan Jong Kim) 강우석(Woo Seok Kang) 김상윤(Sang Yoon Kim)
• 간행물 정보: 『대한두경부종양학회지』제20권 제1호, 3~6쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2004.05.30

영문 초록

Background and Objectives: Nodal metastasis is one of the prognostic factors in salivary gland cancer. The purpose of this study is to identify risk factors of nodal metastasis considered as a predictor of poor prognosis in patients with salivary gland cancer. Material and Methods: The authors retrospectively studied 82 patients with salivary gland cancer who underwent surgery from 1992 to 2002. We analyzed age, sex, tumor size, histologic type and 5-year survival rate to compare patients with and without nodal metastasis. Results: Mean age was 55.4 years, with a male-female ratio of 1 : 1.28. The overall 5-year survival rate was 85.5%. Among the 82 patients, 14 patients had nodal metastasis. There was no nodal metastasis in low grade malignancy. In patients without nodal metastasis, mean age was 52.5 years and the overall 5-year survival rate was 94.2%. In patients with nodal metastasis, mean age was 69.4 years and the overall 5-year survival rate was 42.9%. In patients with less advanced cancer (T1-T2 stage), the nodal metastasis was 7.5% and with advanced cancer (T3-T4 stage), 33.3%. Conclusion: Nodal metastasis significantly decreases survival in patients with salivary gland malignancy. High grade malignancy, large tumor size and old age are important risk factors of nodal metastasis. Nodal metastasis is more common in submandibular gland cancer compared with parotid gland cancer.

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키워드

타액선 종양 예후 림프절 전이 Salivary gland neoplasms Prognosis Lymphatic metastasis