피판 부전증의 구제를 위한 약용거머리 치료법

• 영문명: Medicinal Leech Therapy for Salvage of the Failing Flap
• 발행기관: 대한두경부종양학회
• 저자명: 백정환(Chung Hwan Baek) 신준호(Juno Shin) 박주현(Joo Hyun Park)
• 간행물 정보: 『대한두경부종양학회지』제16권 제1호, 20~25쪽, 전체 6쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2000.05.30

영문 초록

The medicinal leech, Hirudo medicinalis, has been used for salvage of the venous-congested flap following reconstructive surgery, with increasing frequency during the last two decades. Medicinal leech therapy is a safe, efficacious, economical, and well-tolerated intervention. The flap salvage with leeching occurs in approximately 70% of cases, and leeches need to be used as early as possible. At the time of the bite, evacuation of blood and injection of the leech saliva products, including anticoagulants and inhibitors of platelet aggregation, maintain capillary circulation of the flap, and then venous capillary return is established across the wound by angiogenesis. One of the salivary products, hirudin, represents the first parenteral anticoagulant introduced since the discovery of heparin. We analyzed two cases in which flap salvage with leeching was attempted, and reviewed medicinal leech therapy on the basis of our experiences and literature review. This has not been documented in the head and neck surgery literature in our country.

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키워드

Medicinal leech Hirudo medicinalis Hirudin Flap