근치적수술과 술후방사선치료를 받은 이하선 악성종양 환자의 치료실패 양상

• 영문명: Patterns of Failure after Combined Surgery and Radiation Therapy for Malignant Tumors of the Parotid Gland -Analysis of Treatment Results According to Pathologic Type-
• 발행기관: 대한두경부종양학회
• 저자명: 이상욱(Sang Wook Lee) 장세경(Sei Kyung Chang) 김귀언(Gwi Eon Kim) 서창옥(Chang Ok Suh) 성진실(Jin sil Seong) 이창걸(Chang Geol Lee) 금기창(Ki Chang Keum) 박정수(Cheong Soo Park) 최은창(Eun Chang Choi)
• 간행물 정보: 『대한두경부종양학회지』제15권 제2호, 182~188쪽, 전체 7쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1999.11.30

영문 초록

Purpose: To investigate the treatment results' and patterns of failure according to the pathologic type of the parotid malignancy who were treated with radical sugery and postoperative radiation therapy. Materials and Methods: Fifty-two patients with various type of the parotid malignancy, who were treated with combined radical surgery and post-operative irradiation at Yonsei Cancer Center, between 1981 and 1995, were retrospectively reviewed after completion treatment, all but one patients were follow up with the median follow up period of 49 months. Results: We found that pathologically confirmed neck node metastasis rate was 28.8% all case and level II was most common site. Overall failure rate was 26.9%, local recurrence rate was 13.5%, node failure rate was 7.7%, and distant failure rate was 5.8%. Five-year disease free survival rate was 70.9%, and overall survival rate was 73.8%. Recurrence rate was low in adenoid cystic carcinoma and acinic cell carcinoma. However distant metastasis was very high in undifferentiated carcinoma. Local recurrence was main pattern of failure in mucoepidermoid carcinoma and nodal failure was frequently observed in adenocarcinoma. Conclusion: Individualized treatment plan may be required to improve a treatment outcome by pathologic subtype of the parotid malignancy.

목차

Abstract

서론

대상 및 방법

결과

고찰

결론

References

키워드

Parotid gland malignancy Surgery Radiotherapy