두피에 발생한 혈관육종의 수술시 Mapping Biopsy의 유용성

• 영문명: Surgical Treatment of Cutaneous Angiosarcoma of Scalp：Usefulness of Preoperative Mapping Biopsies
• 발행기관: 대한두경부종양학회
• 저자명: 강민구(Min Gu Kang) 박종림(Jong Lim Park) 김명국(Myung Good Kim) 장 학(Hak Chang) 민경원(Kyung Won Minn) 고경석(Kyung Suck Koh)
• 간행물 정보: 『대한두경부종양학회지』제23권 제1호, 37~40쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2007.05.30

영문 초록

Objectives ：Cutaneous angiosarcoma is an infrequent but aggressive neoplasm involving the skin of the face and scalp. Unfamiliarity with the clinical manifestations of cutaneous angiosarcoma frequently leads to misdiagnosis and delay in treatment. Complete surgical resection requires the performance of preoperative staging biopsies to determine the true extent of the neoplasm. Intraoperative frozen section analysis to determine the adequacy of the surgical resection is unreliable due to the high false negative rate. Material and Methods ：In five scalp angiosarcoma cases, mapping biopsies were performed at far from the suspected edge of the neoplasm. On permanent pathology, we obtained tumor free margin with occasional focal involvement of the tumor. Results ：Frozen-section analysis of the resected margins is inconclusive, for the subtle diagnostic features of angiosarcoma are distorted by the tissue processing required for frozen-section analysis. The characteristic dermal vessels lined by their malignant cells are collapsed by the freezing process. This results in a high rate of false-negative reports and possibly leads to incomplete resection of the neoplasm. Conclusion ：Our recommendation is to establish the margins of the tumor by performing preoperative eval-uations by mapping biopsies.

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Scalp angiosarcoma Mapping biopsies Resection margins 두경부 혈관육종 지도상 조직검사 절제 경계.