고압산소요법으로 치료한 뇌기저부 방사선골괴사 1예

• 영문명: Management of Skull Base Osteoradionecrosis with Hyperbaric Oxygen Therapy
• 발행기관: 대한두경부종양학회
• 저자명: 황 은(Eun Hwang) 이종주(Jong Joo Lee) 신유섭(Yoo Seob Shin) 김철호(Chul-Ho Kim)
• 간행물 정보: 『대한두경부종양학회지』제27권 제1호, 66~69쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2011.05.30

영문 초록

Skull base osteoradionecrosis(ORN)is a rare complication of radiotherapy for nasopharyngeal carcinoma, but is one of the most severe and possibly fatal condition followed by radiotherapy. However, the treatment of skull base ORN has seldom been thoroughly described yet. Here we report a case of skull base ORN that was successfully treated with hyperbaric oxygen therapy(HBO). A 52-year-old man visited our department com-plaining of trismus and foul odor. He was diagnosed with nasopharyngeal cancer with multiple lymph node metastasis one year ago and underwent concurrent chemoradiotherapy. On the physical examination, mucopus and crusts with exposed necrotic bone was seen in the right nasopharynx. On the paranasal sinus magnetic resonance imaging, osteoradionecrosis which was extending from the right nasopharynx to the clivus, petrous apex, and cavernous sinus was noted. Nasopharynx biopsy resulted of ulcer with no malignant cells. HBO thera-py was performed with debridement of nasopharynx for 3 months. There was no sign of recurrence or residual ORN 18 months after HBO therapy.

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Osteoradionecrosis Nasopharynx cancer Hyperbaric oxygen therapy 방사선골괴사· 비인강암· 고압산소치료.