양성 갑상선 질환으로 편측 갑상선 절제술을 시행한 후 발생되는 갑상선 기능 저하증에 대한 위험인자

• 영문명: Risk Factors of Hypothyroidism after Hemithyroidectomy for Benign Thyroid Disease in Korea
• 발행기관: 대한두경부종양학회
• 저자명: 이석재(Seok-Jae Lee) 김경태(Kyung-Tae Kim) 조병한(Byung Han Cho) 임재열(Jae-Yol Lim) 김영모(Young-Mo Kim)
• 간행물 정보: 『대한두경부종양학회지』제26권 제2호, 212~215쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2010.11.30

영문 초록

Objectives ：There are various reports for incidence and risk factors of hypothyroidism after hemithyroi-dectomy for benign thyroid disease. The reported incidence rate varies from 5.0 to 41.9%. Moreover, there are few reports about this in Korea. So, our objective is to identify the incidence and possible factors contributing to hypothyroidism after hemithyroidectomy in Korea. Subjectives and Methods ：We reviewed medical re-cords of patients who underwent hemithyroidectomy between 1999 and 2007 years. We enrolled 80 patients. The incidence of postoperative hypothyroidism was based on thyrotropin values and clinical symptoms. And all patients were evaluated for age, gender, serum thyrotropin(TSH) levels, serum free T4, weight of resected thyroid tissue and associated thyroiditis. Results ：Nine of 80 patients(11.3%) became biochemically hypothyroid postoperatively. Six of 9 hypothyroid patients were diagnosed within 2 months of operation. The mean preope-rative TSH level was 2.12±0.96mIU/L in hypothyroid and significantly different from 1.33±0.77mIU/L in euthyroid patients(p<0.05). There were no significant differences in age, gender, weight of resected thyroid tissue, preoperative free T4 and associated thyroiditis. Conclusion ：A minority of patients became hypothyroid after hemithyroidectomy. Hypothyroidism following hemithyroidectomy occurred in patients with higher preo-perative TSH levels.. The screening test for postoperative hypothyroidism should be performed from month to year after operation.

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키워드

Hypothyroidism Hemithyroidectomy 갑상선 기능 저하증 편측 갑상선 절제술.