두경부에 발생한 Progressive Transformation of Germinal Centers(PTGC) 환자 2예

• 영문명: Two Cases of Progressive Transformation of Germinal Centers(PTGC) in Head and Neck Area
• 발행기관: 대한두경부종양학회
• 저자명: 한원규(Won Gue Han) 김태민(Tae Min Kim) 윤희철(Hee chul Yoon) 염건휘(Gun hwee Yum) 오경호(Kyoung Ho Oh) 권순영(oon Young Kwon)
• 간행물 정보: 『대한두경부종양학회지』제31권 제1호, 34~38쪽, 전체 4쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 2015.05.30

영문 초록

Progressive transformation of germinal centers(PTGC) is a rare benign lymph node enlargement characterized by chronic lymphadenopathy and the presence of germinal centers with fused and expanded mantles within a lymph node that are 3-5 times the size of a typical reactive follicle. Although PTGC is reported in 3.5-10% of chronic lymphadenopathy, head and neck surgeons do not often experience this condition and its clinical implications. Al-thoug PTGC is benign disease, it could not be excluded the association with other malignant lymphoid diseases. Therefore, periodic follow up of PTGC patient could be required. We report two cases at this study ; a 16 years old man who visited out-patient clinic due to palpable mass of right cervical area, several months ago, and a 35 years old man who visited out-patient clinic for evaluating right cervical mass. Both of two patients were diagnosed with PTGC. In this study, we focus on the clinic-pathologic features of this uncommon disease along with other literature reviews.

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키워드

Progressive transformation of germinal centers(PTGC) Nodular lymphocyte predominant Hodgkin’s disease(NLPHD) T cell rich B cell lymphoma Nodal marginal zone B cell lymphoma Mantle cell lymphoma 배중심 진행성변이 호즈킨병 T세포 풍부 B세포 림프종 결절성 변연부 B세포 림프종 외투세포림프종.