악성 타액선 종양 114예의 임상고찰

• 영문명: Clinical Analysis of 114 Cases of Malignant Salivary Gland Tumors
• 발행기관: 대한두경부종양학회
• 저자명: 박윤규(Yoon Kyu Park) 설대위(David J Seel) 정동규(Dong Kyu Chung)
• 간행물 정보: 『대한두경부종양학회지』제1권 제1호, 27~34쪽, 전체 8쪽
• 주제분류: 의약학 > 종양학
• 파일형태: PDF
• 발행일자: 1985.10.30

영문 초록

The authors reviewed 114 cases of malignant major and minor salivary gland tumors at Presbγterian Medical Center seen from February, 1963 to December, 1983. The results were obtained as follows; 1) Overall male and female sex ratio was 2 : 1. The peak age of patients with major and minor salivary gland tumor were both 5th decade. 2) The ratio of benign and malignant tumor was 83 : 114. The incidence of malignancy in each group was 52 % in parotid (50 patients), 75% in minor salivary gland (45 patients), 49% in submaxillary gland(18 patients) and 25% in sublingual gland (1 patient). 3) The incidence according to the anatomic primary site for minor salivary cancers was 10 cases in the nasal cavity, each 8 in the palate and the maxillary antrum, 7 in the tongue, 5 in the gum, 3 in the larynx and 2 in the buccal mucosa. 4) Adenoid cystic carcinoma was the most common cancer of minor salivary gland and malignant mixed tumor was the most common in major salivary glands, each comprising 34 cases (76%) of minor and 19 cases (28%) of major salivary gland tumors. 5) The incidence of cervical lymph node metastasis was 50 % in the submaxillary gland cancers, 44% in the parotid gland cancers and 21 % in malignant tumors of minor salivary glands. The highest incidence of lymph node metastasis according to histopathological classification was formed in high grade of mucoepidermoid (67 %). 6) Nerve invasion was common in mucoepidermoid carcinoma. According to anatomic site, nerve invasion occurred most often in adenoid cystic carcinoma of the submaxillary gland (44%). 7) The lung was the commonest site for distant metastasis comprising 12 cases among 26 cases in which distant spread occurred. 8) The recurrence rate was 50% for major salivary gland cancer and 52% in cancer of the minor salivary gland. In accordance with pathological classification, adenocarcinoma most frequently recurred after excision. This being seen in 88% of patients undergoing definitive therapy. 9) The determinate 5 year survival rate was 78% in major salivary gland tumors, but 69 % in minor salivary gland tumors.

목차

ABSTRACT

서론

관찰대상 및 방법

관찰 결과

총괄 및 고안

결론

REFERENCES