광간섭단층촬영기로 구한 시신경 및 망막신경섬유층 측정치들에 영향을 미치는 요인

• 영문명: Factors Influencing Optic Disc and Retinal Nerve Fiber Layer Parameters Measured by Optical Coherence Tomography
• 발행기관: 대한안과학회
• 저자명: 한정일 임한웅 송유미 엄기방,Jung-Il Han, M.D., Han-Woong Lim, M.D., Yoo-Mi Song, M.D., Ki Bang Uhm, M.D.
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number8, 1073~1081쪽, 전체 9쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.08.31

영문 초록

Purpose: To determine the factors influence retinal nerve fiber layer (RNFL) and optic nerve head (ONH) parameters measured by Stratus optical coherence tomography (OCT). Methods: Topographic RNFL thickness and optic disc parameters of 129 healthy Korean subjects of aged 14 to 87 were measured using the fast retinal nerve fiber layer thickness and fast optic disk algorithms of Stratus OCT. One eye of each subject was randomly selected for statistical analysis. Using multiple linear regression, the effect of optic disc area, age, refractive error, and zone beta on each parameter was analyzed. Results: Large discs had large horizontal integrated rim width (HIRW), cup area, rim area, C/D area ratio, and vertical C/D ratio. The thickness of average, superior, inferior, and nasal quadrant RNFL increased significantly with an increase in optic disc area. Average and superior quadrant RNFL thickness, and HIRW decreased with age. Refractive error showed a correlation with the vertical integrated rim area, horizontal C/D ratio, and temporal quadrant RNFL thickness. Gender and zone beta had no statistically significant influence on ONH and RNFL parameters. Conclusions: This study shows that optic disc size affects most RNFL thickness and ONH parameters. Because of the relationships revealed in this study, optic disc area in addition to age should be considered when the Stratus OCT RNFL thickness and ONH parameters are interpreted.

키워드

Normal eye, Optic disc, Retinal Nerve Fiber Layer, Stratus optical coherence tomography