엑스염색체관련 연소망막층간분리의 시력과 안저 소견

• 영문명: Long-term Results of Vision and Fundus Findings in X-linked Juvenile Retinoschisis
• 발행기관: 대한안과학회
• 저자명: 이종주 김정훈 정호경 허장원 김성준 유영석,Jong Joo Lee, M.D., Jeong Hun Kim, M.D., Ho-Kyung Choung, M.D., Jang Won Heo, M.D., Seong-Joon Kim, M.D.,, Young Suk Yu, M.D.,
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume48,number7, 911~918쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2007.07.31

영문 초록

Purpose: To evaluate long-term changes in visual acuity, fundus findings and complications in X-linked juvenile retinoschisis. Methods: A retrospective chart review was conducted on 48 patients diagnosed with X-linked juvenile retinoschisis and followed for a minimum of 12 months. Results: Forty-eight males (mean age 5.7 years) were followed for a mean of 6.3 years. The mean visual acuities were 0.14 at the initial and most recent examinations without significant change (p=0.67). Macular abnormalities were seen in all eyes. Macular lesions varied as follows: decreased foveal reflex (12.5%), typical foveal schisis (77.1%), atrophic change (5.2%), and macula-involving peripheral schisis (5.2%). When patients had different macular findings, the mean visual acuities were significantly different among groups (p≤0.005), except those between the atrophic change group and the macula-involving peripheral schisis group. Peripheral schisis was detected in 66% of patients. The fundus findings were stationary during the follow-up period except in complicated cases with vitreous hemorrhage (15.6%). Conclusions: X-linked juvenile retinoschisis causes bilateral visual acuity loss, affecting maculae. In uncomplicated cases, changes in visual acuity and fundus findings were not significant during the follow-up period.

키워드

Fundus findings, Visual acuity, X-linked juvenile retinoschisis