18F-FDG PET-CT에서 진단된 갑상선 우연종의 악성종양 발견율 및 특징

• 영문명: Characteristics and Detection Rate of Thyroidal Incidentaloma using ¹⁸F-FDG PET-CT
• 발행기관: 대한내분비외과학회
• 저자명: 이강영 고건¹ 김선국¹ 고진철¹ 김행수 최상용 박신희 박용휘² Kang Young Rhee M.D. Gun Koh M.D.¹ Sun Kuk Kim M.D.¹ Jin Chul Koh M.D.¹ Haeng Soo Kim M.D. Sang Yong Choi M.D. Shin Hee Park M.D. and Yong Whi Park M.D.²
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』8권1호, 38~42쪽, 전체 5쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2008.03.30

영문 초록

Purpose: PET-CT is often used to differentiate benign or malignant thyroid incidentalomas. In this retrospective study, we evaluated whether the ¹⁸F-FDG uptake pattern and PET-CT findings improved accuracy over the standardized uptake value (SUV). Methods: ¹⁸F-FDG PET-CT was performed on 2,178 subjects from August, 2004, to October, 2007, in Sung-ae Hospital. PET-CT was performed on 806 patients (37%) with suspected or known nonthyroidal cancer and 1,372 healthy subjects (63%) without a previous history of cancer. We investigated the clinical characteristics of patients, history, standardized uptake value (SUV), ultrasonography, and hormone levels in blood. Thyroidal cancer was confirmed by ultrasonography-guided fine needle aspiration and pathology after thyroid operation. Results: The prevalence of focal thyroid lesions on PET-CT was 8.8% (191/2178). Thyroid cancer confirmation was 7.9% (15/191). The maximum SUV of malignant thyroid lesions were significantly higher than that of benign lesions (7.00±3.08 vs. 4.49±1.84, P＜0.001). Conclusion: PET-CT image interpretation that includes 18F-FDG uptake and SUV is better than PET-CT alone for differentiating benign and malignant lesions. Thyroid cancer risk increases as SUVmax levels increase. (Korean J Endocrine Surg 2008;8:38-42)

키워드

갑상선, 갑상선암, ¹⁸F-FDG PET-CT, SUV, 갑상선 우연종,Thyroid, Thyroid cancer, ¹⁸F-FDG PET-CT, SUV, Incidentaloma