유두상 갑상선암종 환자의 수술요법 후 혈청 타이로글로불린

• 영문명: Postoperative Serum Thyroglobulin in Patients with Papillary Thyroid Carcinoma
• 발행기관: 대한내분비외과학회
• 저자명: 최인석 예병국 한군택 심문섭 In Seok Choi M.D. Byung Kook Yea M.D. Koon Taek Han M.D. and Mun Sup Sim M.D.
• 간행물 정보: 『The Koreran journal of Endocrine Surgery』1권2호, 255~258쪽, 전체 4쪽
• 주제분류: 의약학 > 일반외과학
• 파일형태: PDF
• 발행일자: 2001.10.30

영문 초록

Purpose: Postoperative serial serum thyroglobulin (Tg) measurements on levothyroxine (L-T₄) therapy in patients with differentiated thyroid carcinoma (DTC) is known to be useful in monitoring tumor progression or regression. The objective of this study was to evaluate the significance of serum Tg levels on L-T₄ therapy after surgery. Methods: To determine the basal serum Tg levels on L-T₄ therapy after surgery in patients with DTC, Tg levels during the initial 2 year-period after surgery were analyzed retrospectively in 37 patients who had undergone a total thyroidectomy for papillary thyroid carcinoma with (Group 2) or without (Group 1) palpable cervical lymph node metastasis. The Tg levels had been measured 1 to 4 times for each patient with total of 53 and 35 times in Group 1 and Group 2 respectively. Results: The basal Tg levels in Group 1 were all less than 4 ng/mL with 79.3% less than 2 ng/mL, and those in Group 2 were all less than 9 ng/mL with 71.4% less than 2 ng/mL. Conclusion: The data suggests that the postoperative serum Tg level of 10 ng/mL can be a useful reference value in long-term follow-up after total thyroidectomy for patients with DTC. (Korean J Endocrine Surg 2001;1:255-258)

키워드

타이로글로불린, 유두상 갑상선암, 갑상선전절제술,Thyroglobulin, Papillary Thyroid Carcinoma, Total thyroidectomy