엉겅퀴(Cirsium japonicum var. ussuriense)추출물 및 분획물의 항위염 및 항 위궤양 효과에 대한 연구

• 영문명: Antigastritic and Antiulcerative Effects of Cirsium japonicum var. ussuriense Extract and Fractions
• 발행기관: 대한약학회
• 저자명: 이유미(Yu Mi Lee) 황인영(In Young Hwang) 이은방(Eun Bang Lee) 정춘식(Choon Sik Jeong)
• 간행물 정보: 『약학회지』제55권 제2호 (2011년), 160~167쪽, 전체 8쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2011.04.30

영문 초록

Cirsium japonicum var. ussuriense (CJ) is used as a folk medicine for diuretic, arthritis, dyspepsia, and bleeding in Korea. Until now, more than fifteen kinds of CJ were identified and among them, Cirsium japonicum var. nakaianum Nakai was selected as experimental material. Both that from The Medical Herb Garden of Seoul National University located at Gayang-dong, Koyang city and native that from a hillock near Dangjin, Chungnam were collected and analyzed to determine whether it is varied in efficacy on their habitats. Extracts and fractions of CJ had a strong effect of antibacterial activity on H. pylori and antioxidant effects. And the CJ from Garden and Dangjin were showed to be more efficient in acute gastritis through the HCl·ethanol-induced gastric lesion test and chronic gastritis through the indomethacin-induced gastric lesion test, respectively. This study proved that the effects of CJ are varied by their habitats. Also, these results suggest that the CJ has potentials for use as functional food and medicine.

키워드

Cirsium japonicum var. ussuriense anti-gastritis anti-ulcer anti-oxidant Helicobacter pylori