안와가성종양의 임상양상과 스테로이드 반응성에 대한 분석

• 영문명: Clinical Features and Results of Steroid Therapy for Orbital Inflammatory Pseudotumor
• 발행기관: 대한안과학회
• 저자명: 성미선 오한진 고병이 윤경철,Mi Sun Sung, MD, Han Jin Oh, MD, Byung Yi Ko, MD, PhD, Kyung Chul Yoon, MD, PhD
• 간행물 정보: 『대한안과학회지』Ophthalmological Society,volume54,number2, 185~191쪽, 전체 7쪽
• 주제분류: 의약학 > 기타의약학
• 파일형태: PDF
• 발행일자: 2013.02.28

영문 초록

Purpose: To evaluate the clinical features and treatment outcomes of steroid therapy for orbital inflammatory pseudotumor. Methods: Sixty-four patients diagnosed with orbital inflammatory pseudotumor were reviewed retrospectively. Patients with a follow-up period of less than 6 months were excluded from the study. The pseudotumor was classified into myositic, lacrimal, anterior, diffuse, or apical type according to orbital computed tomography findings. All patients were initially treated with systemic corticosteroids and evaluated for response to the treatment. Treatment outcome was considered a “success” if the patient had complete relief of symptoms with no recurrence, and a “failure” if the patient had no or only partial relief of symptoms or showed relapse. Factors affecting the treatment outcome were analyzed. Results: The most frequent lesion subtype was myositis. Periorbital edema was the most common symptom and was evident in 53.1% of the patients. Thirty-eight patients (59.4%) showed treatment success. Age, sex, bilaterality, and mean follow- up length did not correlate with the treatment outcome. A short interval from symptom onset to treatment time and apical subtype were significantly associated with good steroid response (p < 0.05). Conclusions: In orbital inflammatory pseudotumor, myositis was the most common subtype. A short interval from symptom onset to treatment time and apical subtype were associated with good steroid response.

키워드

Myositis, Orbital inflammatory pseudotumor, Periorbital edema